The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Sep 2012
Decontamination of cephalosporin-resistant Enterobacteriaceae during selective digestive tract decontamination in intensive care units.
Prevalences of cephalosporin-resistant Enterobacteriaceae are increasing globally, especially in intensive care units (ICUs). The effect of selective digestive tract decontamination (SDD) on the eradication of cephalosporin-resistant Enterobacteriaceae from the intestinal tract is unknown. We quantified eradication rates of cephalosporin-resistant and cephalosporin-susceptible Enterobacteriaceae during SDD in patients participating in a 13 centre cluster-randomized study and from a single-centre cohort. ⋯ SDD can successfully eradicate cephalosporin-resistant Enterobacteriaceae from the intestinal tract.