The Journal of antimicrobial chemotherapy
-
J. Antimicrob. Chemother. · Jul 2014
Randomized Controlled TrialComparison of oral amoxicillin given thrice or twice daily to children between 2 and 59 months old with non-severe pneumonia: a randomized controlled trial.
Oral amoxicillin (50 mg/kg/day) thrice daily is the first-line therapy for non-severe childhood pneumonia. Compliance could be enhanced if two daily doses are employed. We assessed the equivalence of oral amoxicillin (50 mg/kg/day) thrice or twice daily in those patients. ⋯ Oral amoxicillin (50 mg/kg/day) twice daily is as efficacious as thrice daily.