The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Mar 2015
Multicenter StudyAntifungal susceptibilities of Candida glabrata species complex, Candida krusei, Candida parapsilosis species complex and Candida tropicalis causing invasive candidiasis in China: 3 year national surveillance.
To define the antifungal susceptibility patterns of the most common non-albicans Candida spp. in China. ⋯ In summary, reduced azole susceptibility was seen among C. tropicalis. Resistance to echinocandins was uncommon.
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J. Antimicrob. Chemother. · Mar 2015
Multicenter StudyRevisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study.
Treatment outcome of MDR-TB is critically dependent on the proper use of second-line drugs as per the result of in vitro drug susceptibility testing (DST). We aimed to establish a standardized DST procedure based on quantitative determination of drug resistance and compared the results with those of genotypes associated with drug resistance. ⋯ The automated DST procedure permits accurate and rapid quantitative resistance profiling of first- and second-line antituberculous drugs. Prospective validation is warranted to determine the impact on patient care.