Neuroscience letters
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Neuroscience letters · Mar 2019
α-Synuclein in salivary extracellular vesicles as a potential biomarker of Parkinson's disease.
Detection of α-synuclein (α-syn) in biological fluids such as saliva may serve as potential biomarker of PD. α-syn pertaining to extracellular vesicles (EVs) has been recently studied in plasma, but not in other biological fluids such as saliva. ⋯ Exosomes are present in PD saliva. The α-synOlig and α-synOlig/α-synTotal ratio in salivary EVs may serve as potential diagnostic biomarkers for PD.