The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis.
Since anecdotal series and small, prospective, controlled trials suggest that mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are desirable. ⋯ In this 24-week trial, mycophenolate mofetil was more effective than intravenous cyclophosphamide in inducing remission of lupus nephritis and had a more favorable safety profile.
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Randomized Controlled Trial Multicenter Study
High-dose acetylcysteine in idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor prognosis. ⋯ Therapy with acetylcysteine at a dose of 600 mg three times daily, added to prednisone and azathioprine, preserves vital capacity and DL(CO) in patients with idiopathic pulmonary fibrosis better than does standard therapy alone.
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Editorial Comment
Antioxidant therapy for idiopathic pulmonary fibrosis.