International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1997
Concomitant boost radiotherapy for squamous carcinoma of the tonsillar fossa.
To assess the efficacy of a concomitant boost fractionation schedule of radiotherapy for treating patients with squamous carcinoma of the tonsillar fossa. ⋯ High rates of local and regional disease control were achieved with the concomitant boost fractionation schedule, with few cases of severe late morbidity. Patients with N2 and N3 neck disease were effectively treated with radiation and the selective use of neck dissections. The concomitant boost schedule is our preferred fractionation approach for treating patients with intermediate stage tonsil cancer who are not participating in our current research protocols.
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1997
Comparative StudyThe structure of radiation oncology in the United States in 1994.
1) to measure the basic structural characteristics of radiation oncology facilities for the entire country, providing census data for January 1, 1994; 2) to allow comparisons by facility type, equipment, or patient load; 3) to allow comparisons of the patterns of equipment and personnel to previous surveys; and 4) to make a preliminary assessment of the geographic distribution of facilities. ⋯ The Facilities Surveys continue to provide a unique source of census data on radiation oncology in the United States, allowing comparisons by facility group and over time.
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1997
Randomized Controlled Trial Clinical TrialPrevention of heterotopic ossification about the hip: final results of two randomized trials in 410 patients using either preoperative or postoperative radiation therapy.
Experimental and clinical data support effectiveness of perioperative radiotherapy to prevent heterotopic ossification after hip surgery or trauma. Since 1987, two prospectively randomized trials were performed in patients with high-risk factors to develop heterotopic ossification: the first (HOP 1) to assess the prophylactic efficacy of postoperative low vs. medium dose radiotherapy, and the second (HOP 2) to assess the prophylactic efficacy of pre vs. postoperative radiotherapy. ⋯ With the exception of a small subgroup of patients with ipsilateral high Brooker Grade III and IV, pre- and postoperative radiotherapy are equally effective to prevent heterotopic ossification about the hip after hip surgery and total hip arthroplasty. Fractionated medium dose radiotherapy resulted in the low
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 1997
Efficacy of a belly board device with CT-simulation in reducing small bowel volume within pelvic irradiation fields.
Acute and chronic small bowel toxicity associated with pelvic irradiation limits dose escalation for both chemotherapy and radiotherapy for rectal cancer. Various surgical and technical maneuvers including compression and belly board devices (BBD) have been used to reduce small bowel volume in treatment fields. However, quantitative dose volume advantages of such methods have not been reported. In this study, the efficacy of BBD with CT-simulation is presented with dose-volume histogram (DVH) analyses for rectal cancer. ⋯ For rectal cancers, small bowel is the dose-limiting structure for acute and chronic toxicity. The use of the BBD should improve the tolerance of aggressive combined modality treatment by reducing the small bowel volume within the pelvis compared to the prone position alone. The BBD provides an easy, economical, comfortable, and noninvasive technique to displace small bowel from pelvic treatment fields. The small bowel volume is dramatically reduced at each dose level. The volume reduction does not correlate with gender, age, weight, pelvic separation, and sequence of radiation treatment vs. surgery.