International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Dec 2004
Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy.
To compare the fits of normal-tissue complication probability (NTCP) models based on rectal dose-wall histograms (DWHs) vs. dose-volume histograms (DVHs) when the two are used to analyze a common set of late rectal toxicity data. ⋯ A consistent, although modest, improvement occurs in the fits of NTCP models to the UTMDACC 2-year late rectal bleeding data when the fit is based on the rectal dose-wall histogram instead of on the dose-volume histogram for entire rectum, including contents.
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Int. J. Radiat. Oncol. Biol. Phys. · Dec 2004
Biologic susceptibility of hepatocellular carcinoma patients treated with radiotherapy to radiation-induced liver disease.
To identify the factors associated with radiation-induced liver disease (RILD) and to describe the difference in normal tissue complication probability (NTCP) between subgroups of hepatocellular carcinoma patients undergoing three-dimensional conformal radiotherapy (3D-CRT). ⋯ Hepatocellular carcinoma patients who were HBV carriers or had Child-Pugh B cirrhosis presented with a statistically significantly greater susceptibility to RILD after 3D-CRT.
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Int. J. Radiat. Oncol. Biol. Phys. · Dec 2004
Comment LetterIn regard to Bogart et al.: 70 Gy thoracic radiotherapy is feasible concurrent with chemotherapy for limited-stage non-small-cell lung cancer: Analysis of cancer and leukemia group B study 39808 (Int J Radiat Oncol Biol Phys 2004;59:460-468).
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Int. J. Radiat. Oncol. Biol. Phys. · Dec 2004
Factors predicting local tumor control after gamma knife stereotactic radiosurgery for benign intracranial meningiomas.
To determine the long-term outcomes and prognostic factors in benign intracranial meningiomas treated with gamma knife stereotactic radiosurgery (GK-SRS). ⋯ This report adds to the literature that supports the efficacy and safety of GK-SRS in the management of patients with benign intracranial meningiomas. Our report identified male patients, patients with a CI <1.4, and tumor size greater than 10 cc to have a worse prognosis. Patients who were treated with less conformal plans to cover the dural tail had better outcomes. Our data clearly demonstrate the need to adequately cover the dural tail in patients treated with GK-SRS for benign intracranial meningiomas.