Indian journal of pathology & microbiology
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Indian J Pathol Microbiol · Jan 2005
Extended spectrum b lactamases (ESBL) in clinical isolates of Klebsiella pneumoniae and Escherichia coli.
The present study was conducted to find the prevalence of Extended spectrum b Lactamase (ESBL) producing strains of Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. Coli) in different clinical samples received at the Department of Microbiology, Medical College Baroda. A total of 187 clinical isolates (106 of K. pneumoniae and 81 of E. ⋯ ESBL was detected in 53 isolates (33 K. pneumoniae and 20 E. coli). Using the interpretative guidelines of the NCCLS, 24% to 27% of the ESBL isolates would have been reported to be susceptible to the 3GC by routine antimicrobial susceptibility methods. DDST was found to be a useful, simple and cost effective test for the detection of ESBL producing strains.