Archives of pathology & laboratory medicine
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Arch. Pathol. Lab. Med. · May 2006
Comparative StudyNeutrophil CD64 is an improved indicator of infection or sepsis in emergency department patients.
Sepsis, affecting millions of individuals annually with an associated high mortality rate, is among the top 10 causes of death. In addition, improvements in diagnostic tests for detecting and monitoring sepsis and infection have been limited in the last 25 years. Neutrophil CD64 expression has been proposed as an improved diagnostic test for the evaluation of infection and sepsis. ⋯ Neutrophil CD64 expression quantitation provides improved diagnostic detection of infection/sepsis compared with the standard diagnostic tests used in current medical practice.