Psychopharmacology
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Randomized Controlled Trial Comparative Study Clinical Trial
Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans.
The availability of the highly selective and specific kappa opioid agonist enadoline provides an opportunity to explore the function of kappa receptors in humans and their potential utility as a target for substance abuse pharmacotherapy development. ⋯ These results are discussed with respect to the potential use and safety of kappa agonists for clinical indications.