Psychopharmacology
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans.
There has been controversy about whether the subjective, behavioral or therapeutic effects of whole plant marijuana differ from the effects of its primary active ingredient, Delta(9)-tetrahydrocannabinol (THC). However, few studies have directly compared the effects of marijuana and THC using matched doses administered either by the smoked or the oral form. ⋯ These results support the idea that the psychoactive effects of marijuana in healthy volunteers are due primarily to THC.