Spine
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Randomized Controlled Trial Clinical Trial
The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial.
A prospective randomized study of the therapeutic effect of intradiscal steroid injection compared to a saline placebo. ⋯ This study demonstrates that intradiscal steroid injections do not improve the clinical outcome in patients with discogenic back pain compared with placebo.
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Randomized Controlled Trial Clinical Trial
Gabapentin is a first line drug for the treatment of neuropathic pain in spinal cord injury.
Prospective, randomized, double blind, placebo-controlled, crossover clinical trial. ⋯ Gabapentin can be added to the list of first-line medications for the treatment of chronic neuropathic pain in spinal cord injury patients. It is a promising new agent and offers advantages over currently available treatments.
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Randomized Controlled Trial Comparative Study Clinical Trial
Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective long-term study comparing fusion and pseudarthrosis.
A prospective, randomized study on patients who underwent posterior lumbar decompression with bilateral posterolateral arthrodesis. ⋯ In patients undergoing single-level decompression and posterolateral arthrodesis for spinal stenosis and concurrent spondylolisthesis, a solid fusion improves long-term clinical results. Benefits of a successful arthrodesis over pseudarthrosis were demonstrated with respect to back and lower limb symptomatology compared with prior shorter-term studies, which indicated no significant difference in clinical outcome between the two groups.
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Randomized Controlled Trial Comparative Study Clinical Trial
Rigid, semirigid versus dynamic instrumentation for degenerative lumbar spinal stenosis: a correlative radiological and clinical analysis of short-term results.
Prospective comparative randomized clinical and radiologic study. ⋯ This comparative study showed that all three instrumentations applied over a short area for symptomatic degenerative spinal stenosis almost equally after surgery maintained the preoperative global and segmental sagittal profile of the lumbosacral spine and was followed by similarly significant improvement of both self-assessment and pain scores. Hardware failure occurred at a low rate following dynamic instrumentation solely without radiologically visible pseudarthrosis or loss of correction. Because of the similar clinical and radiologic data in all three groups and the relative small number of patients that were included in each group, it is difficult for the authors to make any recommendation in favor of any instrumentation.