Spine
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Retrospective review case series. ⋯ Scoliosis developed in 8.7% of patients with Down syndrome. There was a high rate of cardiac surgery within this population. Bracing was ineffective for the majority of the patients treated. Although surgery has a high rate of complications, there was only one patient who underwent reoperation.
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Review
Cost-effectiveness of single-level anterior cervical discectomy and fusion for cervical spondylosis.
Cost-effectiveness analysis with retrospective cost analysis and literature review. ⋯ ACDF with allograft offers a benefit relative to ACDF with autograft at a cost of 496 dollars per QALY. ACDFP has a benefit relative to ACDF with allograft at an approximate cost of 32,560 dollars per QALY. CEA provides a method for comparing the benefits and risks of these three procedures. Further research needs to be performed regarding these procedures, particularly examining the postoperative recovery period.
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The effect of sensory motor learning (SML) on chronic low back pain (CLBP) patients' movement capacity was evaluated with the optoelectronic Posturo-Locomotion-Manual (PLM) test. ⋯ The study shows that the CLBP patients had learned and retained a more efficient behavior. The results suggest that SML is an effective intervention for nonspecific CLBP patients.
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To compare the expression of cytokines and core protein of proteoglycan in the scoliotic concave and convex cartilaginous endplate using immunohistochemical staining. ⋯ There was a significantly higher expression of TGFbeta1 and bFGF, although a lower expression of the core protein on the concave side, which suggests a possible etiological factor or a secondary change in the development of adolescent idiopathic scoliosis.
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A systematic review of the medical literature regarding current intradiscal therapeutic methods. ⋯ Low back pain is an extremely common and potentially debilitating problem. Adding biophysical methods to well-tested biomechanical and newly investigated biomolecular solutions allows for multiple avenues of therapeutic interventions. With future clinical and basic science studies regarding intradiscal therapies forthcoming, we may soon alter our current treatment algorithms for the management of discogenic back pain.