Spine
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Randomized Controlled Trial
The efficacy of rhBMP-2 for posterolateral lumbar fusion in smokers.
Retrospective review of prospectively collected data, as part of an IRB-approved, FDA-regulated, randomized, nonblinded IDE trial of rhBMP-2 matrix for lumbar spinal fusion. ⋯ The results of this study suggest that rhBMP-2 may enhance fusion rate in cigarette smokers undergoing single-level instrumented posterolateral lumbar fusion. Despite the improvement in fusion rate with rhBMP-2, clinical outcomes measures were still adversely affected in smokers.
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Randomized Controlled Trial
Active exercise, education, and cognitive behavioral therapy for persistent disabling low back pain: a randomized controlled trial.
A randomized controlled trial. ⋯ This intervention program produces only modest effects in reducing LBP and disability over a 1-year period. The observation that patient preference for treatment influences outcome warrants further investigation.
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Randomized Controlled Trial
Does shaving the incision site increase the infection rate after spinal surgery?