Spine
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Multicenter Study Clinical Trial
Lumbar vertebral growth is governed by "chondral growth force response curve" rather than "Hueter-Volkmann law": a clinico-biomechanical study of growth modulation changes in childhood spinal tuberculosis.
Vertebral defects were created in a validated 3D finite element model (FEM) to simulate destructive tubercular lesions of increasing severity. Forces in various parts of the spine were then calculated and correlated to deformity progression and growth modulation (GM) changes. ⋯ This is the first study in the current literature to demonstrate that spinal growth follows CGFRC rather than HVL. This observation opens a potential window of opportunity to treat spinal deformities by mechanical GM.
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Randomized Controlled Trial Multicenter Study Comparative Study
ISSLS prize winner: Function After Spinal Treatment, Exercise, and Rehabilitation (FASTER): a factorial randomized trial to determine whether the functional outcome of spinal surgery can be improved.
This was a multicenter, factorial, randomized, controlled trial on the postoperative management of spinal surgery patients, with randomization stratified by surgeon and operative procedure. ⋯ This study found that neither intervention had a significant impact on long-term outcome.
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Randomized Controlled Trial Multicenter Study Comparative Study
Function after spinal treatment, exercise, and rehabilitation: cost-effectiveness analysis based on a randomized controlled trial.
Cost-effectiveness analysis alongside a factorial randomized controlled trial. ⋯ Cost-effectiveness evidence does not support use of booklet over no booklet or rehabilitation over no rehabilitation for the postoperative management of patients after spinal surgery.
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Multicenter Study Comparative Study
Fixation points within the main thoracic curve: does more instrumentation produce greater curve correction and improved results?
Prospective consecutive multicenter case series. ⋯ Absolute curve correction improved most with all pedicle screw and screw and wire constructs, but, when compared to bending films, the number of fixation points is more important than fixation type for curve correction. Although SRS scores improved the most in those with all screw constructs, the significance of this improvement is uncertain, and the SRS scores did not relate to whether curve correction was more or less than the bend films.
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Multicenter Study
Risk factors for medical complication after lumbar spine surgery: a multivariate analysis of 767 patients.
Multivariate analysis of prospectively collected registry data. ⋯ Risk factors identified in this study can be beneficial to clinicians and patients alike when considering surgical treatment of the lumbar spine. Future analyses and models that predict the occurrence of medical complication after lumbar spine surgery may be of further benefit for surgical decision making.