Spine
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Multicenter Study Comparative Study
Reliability and accuracy analysis of a new semiautomatic radiographic measurement software in adult scoliosis.
Radiographic software measurement analysis in adult scoliosis. ⋯ The majority of the measures, which were analyzed in this study demonstrated good to excellent reliability and accuracy. The novel semiautomatic measurement software can be recommended for use for clinical, research or multicenter study purposes.
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Randomized Controlled Trial Multicenter Study Comparative Study
Differences in the relationship between psychosocial distress and self-reported disability in patients with chronic low back pain in six pain rehabilitation centers in the Netherlands.
A cross sectional multicenter study in six outpatient Rehabilitation Centers (RCs) in the Netherlands. ⋯ The overall relationship between psychosocial distress and self reported disability was weak, and differences between RCs were considerable. This indicates that the relationship between psychosocial distress and disability in patients with CLBP is not uniform.
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Comparative Study
Changes in spinal cord expression of fractalkine and its receptor in a rat model of disc herniation by autologous nucleus pulposus.
Behavior, mRNA and immunohistochemical assessment of the expression of fractalkine (CX3CL1) and its receptor (CX3CR1) in a rat model of disc herniation by autologous nucleus pulposus (NP) implantation. ⋯ Our results indicate that autologous implantation of NP induces thermal hyperalgesia and mechanical allodynia, and leads to an upregulation of fractalkine and its receptor in spinal neurons and glia, implicating fractalkine in association with radicular pain.
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Comparative Study
The course of work absenteeism involving neck pain: a cohort study of Ontario lost-time claimants.
Cohort study. ⋯ Most injured workers who make a workers' compensation claim that involves neck pain do not make a second claim in the subsequent 2 years. However, an important minority (14.2%) experience multiple episodes of work absenteeism and these workers accrue 40.4% of all lost-time days. Recurrent claims involving neck pain represent a significant burden of disability in Ontario.
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The mechanisms of apoptosis behind the formation of tissue reactions at the surface of the dorsal root ganglion (DRG) exposed to the nucleus pulposus were studied with special reference to the role of interleukin-6 (IL-6), using electron microscopy and immunohistochemistry in rats. ⋯ IL-6 seemed to induce TNF-α at the surface of DRG exposed to IL-6 and to induce a characteristic reaction at the surface of the DRG. IL-6 may thus play an important role in nucleus pulposus-induced apoptosis of the DRG neurons as well as TNF-α.