Spine
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A cross-sectional study of 96 patients with lumbosacral adolescent spondylolisthesis. ⋯ LSK is significantly correlated to the physical aspect of the quality of life of adolescents with spondylolisthesis. The implication of abnormal LSK is particularly evident in patients with high-grade spondylolisthesis. All evaluated LSK parameters seem equivalent to measure this effect. LSK should be routinely measured in adolescents with spondylolisthesis to fully appreciate the severity of the deformity and its clinical association with the quality of life of the patient.
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A cross-sectional study. ⋯ Positive personality characteristics could play a crucial role in patient adjustment, and thus clinicians should take into account the positive path to capacity to better understand the chronic pain experience.
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Retrospective observational study utilizing prospectively collected population-based data. ⋯ The incidence of TSCI in our population has remained remarkably stable, and age-related changes mirror those in the population across 10 years. An increased tendency to surgical treatment during the 10 years of this study has not resulted in concomitant changes in patients' in-hospital mortality or length of stay.
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An in vitro study using ovine intervertebral discs to correlate the effects of increasing advanced glycation end-products (AGEs) with disc hydration evaluated by magnetic resonance imaging (MRI). ⋯ This study demonstrates that levels of AGEs in the IVD may affect the tissue water content. Moreover, these ribosylation-mediated changes in tissue hydration were detectable using T2 relaxation MRI. T2 relaxation MRI may provide a noninvasive tool to measure in vivo changes in disc hydration that are negatively correlated with the accumulation of AGEs.
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In vitro cadaveric study of thoracic spinal cord intramedullary pressure (IMP) in kyphotic deformity. ⋯ Thoracic kyphosis less than +51° resulted in no meaningful increase in IMP, whereas kyphosis measuring +51° to +63° resulted in minor increases in IMP. After the thoracic kyphosis exceeded +63°, IMP increased significantly. ΔIMP with spinal alignment may help explain the wide range of "normal" thoracic neutral upright sagittal alignment in studies of asymptomatic adult individuals and may help further define thoracic kyphotic deformity.