Spine
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Observational and quantitative study with 3-dimensional (3D) computerized tomographic (CT) analysis. ⋯ Instability at the C1-C2 junction in congenital anomaly with occipitalization is likely a direct result of the anteversion of LAA and bony malformation of this region, and it aggratates with the increasing obliquity of anteversion of the AAF. Demonstrating 3D morphological changes of LAA may provide a new means to diagnosis instability in congenital anomaly at craniovertebral junction and a basis for rational surgical treatment.
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In this study, the effect of calcitonin on lumbar spinal fusion was studied in a New Zealand rabbit model. ⋯ Calcitonin can enhance lumbar spinal fusion. One mechanism might be through upregulating genes involved in osteogenesis and angiogenesis.
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Comparative Study
Differences in damage to CGRP immunoreactive sensory nerves after two lumbar surgical approaches: investigation using humans and rats.
Immunohistochemical study. ⋯ There are more CGRP-immunoreactive sensory nerve fibers and DRG neurons innervating muscle in the midline approach area than in the Wiltse paraspinal approach area in humans and rats. There are more ATF-3-immunoreactive DRG neurons innervating muscle in the midline approach area than in the Wiltse paraspinal approach area after muscle injury in rats. This result may show the differences in sensory nerve injury during the 2 surgical approaches.