Spine
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Case report. ⋯ The remaining mobility at the nonossified lesion, where the point of the beak-type OPLL compressed the spinal cord, might have caused the myelopathy in this patient. We propose that stabilization with PSI stimulates bone remodeling of nonossified lesions, leading to a reduction of OPLL. This finding provides a clue about the mechanisms responsible for neurological improvement after PSI for T-OPLL.
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Retrospective analysis. ⋯ 3.
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Animal study. ⋯ Our results indicate that nerve compression plus NP application produces the most pain-related behavior. CGRP-IR nerve terminals increased in laminae I and II that transmit pain and in laminae III to VI that transmit proprioception. Findings suggest that nerve compression plus NP application induces changes in CGRP expression in the superficial and deep laminae, and these changes are partly responsible for disc herniation pain.
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Randomized Controlled Trial Comparative Study
Postoperative pain and long-term functional outcome after administration of gabapentin and pregabalin in patients undergoing spinal surgery.