Spine
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Experimental animal study. ⋯ We demonstrated that long-term mechanical stress caused LF hypertrophy with progressive elastic fiber disruption and cartilage matrix production accompanied by enhanced myofibroblasts. In addition, the reported rabbit model could be extended to elucidate the mechanism of LF hypertrophy and to develop new therapeutic strategies for LSS by preventing LF hypertrophy.Level of Evidence: SSSSS.
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Randomized Controlled Trial Multicenter Study
Predictive Factors Affecting Surgical Outcomes in Patients With Degenerative Lumbar Spondylolisthesis.
Post-hoc analysis of 5-year follow-up data from a prospective randomized multicenter trial. ⋯ While the degree of vertebral slippage and the presence of angulation were not associated with poor recovery after surgery for lumbar degenerative spondylolisthesis, postoperative outcomes were associated with the intervertebral angle and the presence of translation. Careful preoperative measurement of these factors may help to predict poor postoperative outcomes.Level of Evidence: 3.
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Multicenter Study Comparative Study
A Comparison of Three Different Positioning Techniques on Surgical Corrections and Post-operative Alignment in Cervical Spinal Deformity (CD) Surgery.
Retrospective review of a prospective multicenter cervical deformity database. ⋯ Postoperative cervical sagittal correction or alignment was not affected by patient position. The majority of segmental correction occurred at C4-5-6 across all positioning methods, while bivector traction had the largest corrective ability at the cervicothoracic junction.Level of Evidence: 4.