Spine
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A secondary analysis of data from the NORDSTEN-spinal stenosis trial (SST). ⋯ Up to 2 years postoperatively, the DSCA did not decrease at adjacent levels after decompressive surgery. None of the investigated baseline variables showed any clinical meaningful prognostic value regarding adjacent DSCA changes 2 years postoperatively. The findings support previous reports that decompression of adjacent levels is not required to prevent subsequent stenosis.
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Retrospective analysis of prospectively-collected data. ⋯ In complex ASD surgery, intraoperative EBL of 2.3 liters and an EBVL of 42% are associated with clinically-significant AEs. These thresholds may be useful in guiding preoperative-patient-counseling, healthcare system quality initiatives, and clinical perioperative bloodloss management strategies in patients undergoing complex spine surgery. Additionally, similar methodology could be performed in other specialties to establish procedure-specific clinically-relevant bloodloss thresholds.
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Systematic Review and Network-Meta-analysis. ⋯ Antibiotic therapy for 4-8 weeks may provide the optimal balance of efficacy and treatment duration for most patients with primary osteomyelitis discitis. However, treatment should be individualized based on clinical response. Further prospective studies are needed to clarify optimal management strategies for this complex condition.
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Retrospective cohort study. ⋯ 3.