Spine
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Claims-based analysis of cohorts of TRICARE Prime beneficiaries. ⋯ We found substantial variability across catchment areas within TRICARE for the treatment of LBP. Higher rates of opioid prescription were associated with worse outcomes.
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A mouse study of the Slc7a5 gene using conditional knockout to assess the effects of its inactivation on spinal deformity. ⋯ In Sko mice, the characteristics of scoliosis and vertebral pathology showed many similarities with syndromic scoliosis in humans. Endochondral ossification defects may impair growth, leading to scoliosis and decreased BMD.
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Meta Analysis Comparative Study
Comparison of the Safety of Inpatient versus Outpatient Lumbar Fusion: A Systematic Review and Meta-Analysis.
Systematic Review and Meta-analysis. ⋯ Preliminary data regarding the safety of outpatient lumbar fusion demonstrates a favorable safety profile in appropriately selected patients, with PROMs remaining comparable in this setting. There is no data in the form of prospective and randomized trials which is necessary to definitively change practice.
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Cross-sectional and retrospective cohort study. ⋯ Level III.
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This was a retrospective study. ⋯ 3.