Spine
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Basic science study using a hemisection spinal cord injury (SCI) model. ⋯ OPN demonstrates a protective influence against motor function impairment and neuropathic pain following SCI. This phenomenon may result from the proangiogenetic effect of OPN, possibly due to activation of the VEGF and/or AKT pathways.
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Meta Analysis Comparative Study
The Statistical Fragility of Trials Comparing Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion: A Meta Analysis.
Meta-analysis. ⋯ RCTs comparing ACDF and CDA have fair to moderate statistical robustness and do not suffer from statistical fragility.
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Retrospective analysis of prospectively collected data from the National Swedish Spine Register (Swespine). ⋯ A surgically evacuated SSEH does not affect the outcome in terms of back/leg pain or health-related quality of life. Commonly used PROM surveys may not capture neurological deficits associated with SSEH.