Neurochemical research
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Neurochemical research · Jul 1989
Triiodothyronine bound to red blood cells is not available for transport through the blood-brain barrier.
Many steroid and thyroid hormones and some drugs are bound by circulating red cells. Red cell-bound ligand may not be physiologically inert, as recent studies show that red cell-bound drug is available for uptake by brain. ⋯ The fraction of circulating T3 available for uptake in vivo in the presence of 0, 2, 5, 10, 22, or 44% red cells was essentially identical to the fraction of [125I]T3 unbound in vitro. Therefore, [125I]T3 bound to red cells obtained from normal volunteers is not available for uptake by brain in vivo.
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Neurochemical research · Sep 1987
Historical ArticleA long way from the wilderness: thirty memorable years of the Japanese Neurochemical Society.
The history and antecedents of the Japanese Neurochemical Society (JSN) are described. Particulars of the founding in 1958, and of the formal establishment in 1962, are given, together with an outline and description of the JSN's recent activities, including its contributions to the 4th International Meeting of the International Society for Neurochemistry (ISN) in Tokyo in 1973. Suggestions are made for the development of a perspective, and for the promotion, of the ultimate, fundamental purposes of neuroscience, and for the proper internalization of the JSN.