Indian journal of dermatology, venereology and leprology
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Indian J Dermatol Venereol Leprol · Nov 2010
ReviewPsoriasis: what is new in nonbiologic systemic therapy in the era of biologics?
Psoriasis is a common debilitating disease significantly affecting the quality of life of the patients. Majority of the psoriasis patients have mild disease which can be managed by topical therapies. Around 30% of the psoriasis patients require systemic therapy during the course of their disease. ⋯ Newer studies provide insight into their more effective and safer use and as combination therapy with biologics. In recent times, many new drugs with novel mechanisms of action other than biologics have been tried in psoriasis. In this article, we have reviewed the current developments and new found role of the conventional drugs as well as the newer nonbiologic systemic drugs in the treatment of psoriasis.
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Indian J Dermatol Venereol Leprol · Nov 2010
ReviewNewer trends in the management of psoriasis at difficult to treat locations: scalp, palmoplantar disease and nails.
Psoriasis is a common, chronic, inflammatory disease with a wide range of clinical presentations. The disease severity ranges from mild to severe. Plaque type of psoriasis is the most common. ⋯ Psoriasis localized to certain areas of the body like scalp, nails, palms and soles remains difficult to treat. These sites have been referred to as the difficult locations in literature. This article covers the management of psoriasis limited to these special areas.