Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Jun 2003
Corneal innervation and morphology in primary Sjögren's syndrome.
To analyze the in vivo morphology of the different corneal sublayers and corneal nerves in primary Sjögren's syndrome (SS). ⋯ In SS, the corneal surface epithelium was irregular and patchy. Anterior keratocytes frequently showed morphologic features of activation. The subbasal nerve fiber bundles revealed abnormal morphology, and the central corneal thickness was reduced by stromal thinning. The findings confirm epithelial, stromal, and neural abnormalities in the corneas of patients with SS.