Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Apr 2012
Comparative StudyNasal ciliary beat frequency and beat pattern in retinal ciliopathies.
The cilium in photoreceptors appears ultrastructurally very similar to the nasal ciliated epithelium. The purpose of this study was to evaluate the nasal ciliary beat frequency and beat pattern in patients with retinitis pigmentosa (RP) and Usher syndrome type II and compare it with that of healthy control subjects. ⋯ The nasal CBF is diminished in patients with Usher syndrome type II, whereas it remains normal in simplex RP patients. These results add evidence to the fact that Usher syndrome could be a primary ciliary disorder.