Investigative ophthalmology & visual science
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Invest. Ophthalmol. Vis. Sci. · Sep 2013
Comparative StudyGene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma.
To identify the specific genes in human trabecular meshwork (TM) related to POAG. ⋯ This is the largest TM expression study of POAG cases and controls performed to date and represents the first report of TM expression in a patient having POAG with a Q368X MYOC mutation. Our data suggest the potential role of endocytic and exosome pathways in the pathogenesis of POAG.