Journal of computer assisted tomography
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J Comput Assist Tomogr · Nov 2011
Comparative StudyCan the patient with cirrhosis be imaged for hepatocellular carcinoma without gadolinium?: Comparison of combined T2-weighted, T2*-weighted, and diffusion-weighted MRI with gadolinium-enhanced MRI using liver explantation standard.
This study aimed to evaluate a non-gadolinium-enhanced magnetic resonance imaging (MRI) protocol including T2-weighted, T2*-weighted, and diffusion-weighted MRI sequences for identifying hepatocellular carcinoma (HCC) with liver explantation as the reference standard. Also, a stand-alone pre- and dynamic post-gadolinium-enhanced liver MRI data set was interpreted from the available patient data for relative comparison purposes. ⋯ Non-gadolinium-enhanced MRI had a moderate sensitivity for HCC but had a high specificity. Although non-gadolinium-enhanced MRI cannot be recommended as a primary imaging approach for HCC, the results demonstrate the contribution of non-gadolinium-enhanced sequences to imaging of HCC. A non-gadolinium-enhanced MRI protocol may have a diagnostic value when gadolinium cannot be administered.
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J Comput Assist Tomogr · Sep 2011
New spatiotemporal features for improved discrimination of benign and malignant lesions in dynamic contrast-enhanced-magnetic resonance imaging of the breast.
The objective of this study was to measure the efficacy of 7 new spatiotemporal features for discriminating between benign and malignant lesions in dynamic contrast-enhanced-magnetic resonance imaging (MRI) of the breast. ⋯ Results of the experiments suggest that suspicious lesions in dynamic contrast-enhanced-MRI of the breast can be classified, with high accuracy, using only 2 of the proposed spatiotemporal features. The selected features indicate heterogeneity of enhancement and speed of enhancement in a tissue. High values of these indicators are likely to be correlated with malignancy.
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J Comput Assist Tomogr · Jul 2011
Review Case ReportsSurfer's myelopathy-demonstrated by diffusion-weighted magnetic resonance imaging: a case report and literature review.
The authors present a case of "surfer's myelopathy," a rarely described syndrome characterized by nontraumatic paraparesis/paraplegia in novice surfers and theorized to result from spinal cord ischemia secondary to surfing-related positional hyperextension. Imaging and clinical course of the youngest known affected individual are discussed, including evidence of acute spinal cord infarction on diffusion-weighted magnetic resonance imaging, a finding not previously described in the literature.
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J Comput Assist Tomogr · May 2011
ReviewIs there a role for fluorine 18 fluorodeoxyglucose-positron emission tomography and positron emission tomography/computed tomography in evaluating patients with mycobacteriosis? A systematic review.
This study was designed to review the emerging role of fluorine 18 fluorodeoxyglucose (¹⁸F-FDG)-positron emission tomography (PET) CT/computed tomography (PET/CT) in patients with mycobacteriosis. ⋯ (1) Mycobacteriosis commonly causes increased ¹⁸F-FDG uptake; therefore, positive ¹⁸F-FDG-PET results should be interpreted with caution in differentiating benign from malignant abnormalities. (2) ¹⁸F-FDG-PET and PET/CT are potentially useful in detecting sites of Mycobacterium infection. (3) Dual-phase ¹⁸F-FDG-PET is not useful for the differential diagnosis between malignant lesions and sites of Mycobacterium infection. (4) ¹⁸F-FDG-PET and PET/CT are useful for the evaluation of disease activity and in monitoring response to therapy in patients with mycobacteriosis. (5) Dual-tracer PET and PET/CT are potentially useful for presumptive diagnosis of solitary pulmonary nodules.
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J Comput Assist Tomogr · Mar 2011
Randomized Controlled Trial Comparative StudyProspective randomized trial of iohexol 350 versus meglumine sodium diatrizoate as an oral contrast agent for abdominopelvic computed tomography.
To compare the efficacy and patient tolerance of iohexol and meglumine sodium diatrizoate as oral contrast agents for computed tomography (CT). ⋯ Iohexol 350 is a satisfactory oral contrast agent for abdominopelvic CT. It opacifies the gastrointestinal tract as well as meglumine sodium diatrizoate does, and patients prefer the taste of iohexol to that of diatrizoate.