Microbiology and immunology
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Microbiol. Immunol. · Oct 2011
Analysis of peripheral blood lymphocyte subsets and prognosis in patients with septic shock.
The purpose of the study is to study the relationship between peripheral blood lymphocyte subset proportion and prognosis in patients with septic shock. Fifty-two patients with septic shock, admitted to the intensive care unit between March 2007 and December 2010, were enrolled in this study. Peripheral blood lymphocyte subset proportions were measured using flow cytometry. ⋯ The total maximum SOFA score and the delta SOFA score were much higher in the non-survivor group than in the survivor group (P < 0.01). Immune imbalance occurs in patients with septic shock. Peripheral blood lymphocyte subset proportion and SOFA scores can be used to assess the treatment and prognosis of septic shock.