World journal of surgery
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Surgical risk increases with age, primarily from loss of cardiac and pulmonary reserve. Complications are tolerated poorly by the elderly, emphasizing the importance of their prediction and prevention. ⋯ Risk assessment based on validated tools is utilized, and perioperative management recommendations based on the state of the art are examined. In addition, pulmonary embolism and postoperative confusion are examined separately with the same overall strategy.
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Treatment of postoperative pain has not received sufficient attention by the surgical profession. Recent developments concerned with acute pain physiology and improved techniques for postoperative pain relief should result in more satisfactory treatment of postoperative pain. Such pain relief may also modify various aspects of the surgical stress response, and nociceptive blockade by regional anesthetic techniques has been demonstrated to improve various parameters of postoperative outcome. It is therefore stressed that effective control of postoperative pain, combined with a high degree of surgical expertise and use of other perioperative therapeutic interventions including nutrition and mobilization, should be combined to improve overall perioperative care and surgical outcome.
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World journal of surgery · Mar 1993
Predicting postoperative fatigue: importance of preoperative factors.
Postoperative fatigue as defined by a 10-point scale (1 = fit, 10 = fatigued) was determined prospectively in 84 patients undergoing major surgery. Results from this scale correlated well with standard psychological assessment of fatigue (Profile of Mood States Questionnaire) (r = 0.767; p < 0.0001). Fatigue values were 3.46 +/- 0.19 arbitrary units (mean +/- SEM) preoperatively; and postoperatively they were 5.61 +/- 0.24 at day 7, 5.02 +/- 0.24 at day 14, 3.74 +/- 0.19 at day 28, and 2.77 +/- 0.18 at day 90. ⋯ The best predictor of postoperative fatigue was preoperative fatigue (r = 0.545; p = 0.001), with lesser correlations with diagnosis (especially cancer); preoperative weight, particularly total body protein (r = 0.317; p = 0.01); and weight loss (r = 0.29; p = 0.03), grip strength (r = 0.352; p = 0.01), and age (r = 0.267; p = 0.01). Postoperative fatigue was not correlated with preoperative anxiety, depression, or hostility, involuntary muscle function, gender, preoperative stress, or changes in total body protein or fat over the two postoperative weeks. It is concluded that patients who present for surgery already fatigued are the ones who are most likely to suffer from prolonged postoperative fatigue, particularly so if they are elderly, suffer from cancer, or have few extra reserves of body protein.