World journal of surgery
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World journal of surgery · Jul 2005
Case ReportsDopamine-secreting pheochromocytomas: in search of a syndrome.
Pheochromocytomas rarely produce dopamine as the only catecholamine. Two cases are reported here, and a review of the literature was conducted. Unlike norepinephrine-and epinephrine-secreting tumors, dopamine-secreting pheochromocytomas lack a classic clinical presentation and are often asymptomatic. ⋯ This medication is an option for controlling symptoms but should not be used routinely in these patients. The prognosis for patients with these tumors is worse than for those with an epinephrine- and norepinephrine-secreting tumor. Because of their asymptomatic nature, dopamine-secreting pheochromocytomas tend to be detected later and are more likely to be malignant at the time of diagnosis.
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World journal of surgery · Jul 2005
Perforated peptic ulcer treated by simple closure and Helicobacter pylori eradication.
Simple closure followed by Helicobacter pylori (Hp) eradication has become the most used procedure in perforated ulcer treatment. However, its efficacy and safety are still to be determined. To assess recurrence and re-perforation rates, and as a secondary objective, to analyze Hp infection rates in perforated ulcer patients and controls, we conducted a prospective study. ⋯ Overall relapse and re-perforation 1-year crude rates were 6.1% and 4.1%, respectively. Crude rates for non-gastric ulcer recurrence were 0 at 1 year and 2.6% at 2 years and for non-gastric ulcer re-perforation rates were 0 at 1 and 2 years. This therapeutic strategy is associated with a low rate of recurrence and no re-perforations in case of duodenal, pyloric, or pre-pyloric perforated ulcers, but it is not acceptable for perforated gastric ulcers.