Intensive care medicine
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Intensive care medicine · May 1995
Randomized Controlled Trial Clinical TrialRespiratory mechanics by least squares fitting in mechanically ventilated patients: applications during paralysis and during pressure support ventilation.
To evaluate a least squares fitting technique for the purpose of measuring total respiratory compliance (Crs) and resistance (Rrs) in patients submitted to partial ventilatory support, without the need for esophageal pressure measurement. ⋯ The LSF method allows non-invasive evaluation of respiratory mechanics during PSV, provided that a near-relaxation condition is obtained by means of an adequately increased pressure support level. The measurement of P0.1 may be helpful for titrating the pressure support in order to obtain the condition of near-relaxation.