Intensive care medicine
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Intensive care medicine · Mar 1998
Randomized Controlled Trial Clinical TrialThe effect of N-acetylcysteine on total serum anti-oxidant potential and urinary albumin excretion in critically ill patients.
To investigate the effects of N-acetylcysteine (NAC) when given as an early treatment to critically ill patients on the serum total anti-oxidant potential (TAP) and urine micro-albumin:creatinine (M:Cr) ratio. ⋯ Our results suggest that NAC had no significant effects on the progress of the TAP and the urinary albumin excretion in our patients, which may suggest that NAC at the given dose has no clinical relevance as an early treatment in the critically ill.
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Intensive care medicine · Mar 1998
Implementation of a clinical practice guideline for stress ulcer prophylaxis increases appropriateness and decreases cost of care.
To develop, implement and evaluate a practice guideline for stress ulcer prophylaxis. ⋯ Introduction of this guideline was associated with an increase in appropriateness of prophylaxis and a decrease in medication costs.