Intensive care medicine
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Intensive care medicine · Jul 2000
Multicenter StudyAcute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score.
To describe risk factors for the development of acute renal failure (ARF) in a population of intensive care unit (ICU) patients, and the association of ARF with multiple organ failure (MOF) and outcome using the sequential organ failure assessment (SOFA) score. ⋯ In ICU patients, the most important risk factors for ARF or mortality from ARF are often present on admission. During the ICU stay, other organ failures (especially cardiovascular) are important risk factors. Oliguric ARF was an independent risk factor for ICU mortality, and infection increased the contribution to mortality by other factors. The severity of circulatory shock was the most important factor influencing outcome in ARF patients.
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Intensive care medicine · Jul 2000
Randomized Controlled Trial Clinical TrialParenteral with enteral nutrition in the critically ill.
To determine whether nutrient intake by early enteral nutrition with parenteral nutrition improves levels of retinol-binding protein and prealbumin (primary endpoint) and reduce morbidity and mortality (secondary endpoint) in ICU patients. ⋯ Although it enhances nutrient intake and corrects nutritional parameters such as RBP and prealbumin more rapidly, within 1 week, supplemental parenteral nutrition has no clinically relevant effect on outcome in ICU patients at the early phase of nutritional support.
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Intensive care medicine · Jul 2000
Multicenter Study Clinical TrialDiastolic function in neonates after the arterial switch operation: effects of positive pressure ventilation and inspiratory time.
To determine the effects positive pressure ventilation have on left ventricular diastolic function in neonates after the arterial switch operation. ⋯ In neonates with transposition of the great arteries (TGA) after the arterial switch operation, positive pressure ventilation augments left ventricular filling during the early phase of inspiration. Prolonging the inspiratory time over three cardiac cycles results in a reduction in left ventricular filling during the third diastolic period. There were no changes in the other diastolic indexes that reflect changes in ventricular compliance or relaxation.
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Intensive care medicine · Jul 2000
Association of PEEP with two different inflation volumes in ARDS patients: effects on passive lung deflation and alveolar recruitment.
To assess the effects of the association of positive end-expiratory pressure (PEEP) with different inflation volumes (V(T)'s) on passive lung deflation and alveolar recruitment in ARDS patients. ⋯ In mechanically ventilated ARDS patients: (a) the behavior of airway resistance seems to depend on the degree of the prevailing lung distension; (b) alveolar recruitment appears to be more important when higher tidal volumes are used during mechanical ventilation on PEEP; (c) PEEP changes the mechanical properties of the respiratory system fast-emptying compartment.