Intensive care medicine
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Intensive care medicine · Dec 2001
Randomized Controlled Trial Comparative Study Clinical TrialEndocrine effects of dopexamine vs. dopamine in high-risk surgical patients.
To compare the endocrine effects of dopexamine and dopamine on prolactin (PRL), dihydroepiandrosterone sulfate (DHEAS), cortisol, thyrotropin (TSH), and peripheral thyroid hormone serum concentrations in surgical patients at risk of developing postoperative complications because of hypoperfusion of various organ systems. ⋯ Routine postoperative optimizing of men undergoing abdominal surgical procedures with dopexamine at higher doses or dopamine induces at least partial hypopituitarism, which may possibly affect postoperative morbidity.