Intensive care medicine
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Intensive care medicine · Apr 2002
Review Randomized Controlled Trial Clinical TrialRelationship between ventilatory settings and barotrauma in the acute respiratory distress syndrome.
High pressures or volumes may increase the risk of barotrauma in the acute respiratory distress syndrome (ARDS). ⋯ Clinical studies maintaining P(plat) lower than 35 cmH(2)O found no apparent relationship between ventilatory parameters and pneumothorax. Analysis of the literature suggests a correlation when patients receive mechanical ventilation with P(plat) levels exceeding 35 cmH(2)O.
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Intensive care medicine · Apr 2002
Randomized Controlled Trial Clinical TrialSelective decontamination of subglottic area in mechanically ventilated patients with multiple trauma.
To determine whether selective decontamination locally in the subglottic area (SDSA) reduces tracheal colonization and prevents ventilator-associated pneumonia (VAP) in patients with multiple trauma. ⋯ The SDSA is an effective and safe type of chemoprophylaxis against tracheal colonization and can significantly reduce the incidence of VAP in mechanically ventilated patients with multiple trauma.