Intensive care medicine
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Intensive care medicine · Nov 2006
Multicenter StudyPredictors of early recovery of health status after intensive care.
To identify factors predictive of good or poor recovery of health status and health-related quality of life (HRQOL) 90 days after admission to an intensive care unit (ICU). ⋯ More than 60% of ICU patients report good recovery of their health 90 days after ICU admission, depending on their illness and circumstances of ICU admission.
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Intensive care medicine · Nov 2006
Randomized Controlled Trial Multicenter Study Comparative StudyVasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial.
To compare the effects of arginine-vasopressin (AVP) and norepinephrine (NE) on hemodynamic variables, organ dysfunction, and adverse events in early hyperdynamic septic shock. ⋯ In early hyperdynamic septic shock, the administration of high-dose AVP as a single agent fails to increase mean arterial pressure in the first hour but maintains it above 70mmHg in two-thirds of patients at 48h. AVP decreases NE exposure, has no effect on the PrCO(2) - PaCO(2 )difference, and improves renal function and SOFA score.
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Intensive care medicine · Nov 2006
Monitoring dead space during recruitment and PEEP titration in an experimental model.
To test the usefulness of dead space for determining open-lung PEEP, the lowest PEEP that prevents lung collapse after a lung recruitment maneuver. ⋯ Monitoring of dead space was useful for detecting lung collapse and for establishing open-lung PEEP after a recruitment maneuver.
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Intensive care medicine · Nov 2006
Alveolar recruitment assessed by positron emission tomography during experimental acute lung injury.
To compare changes in aerated lung volumes measured by positron emission tomography (PET) and inflation volume-pressure curve (V-P) of the respiratory system, and to evaluate the reliability of PET to assess alveolar recruitment. ⋯ PET is a new reliable tool of scientific interest to image lung volume and alveolar recruitment during acute lung injury.
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Intensive care medicine · Nov 2006
Multicenter Study Comparative StudyMechanism of injury influences quality of life in survivors of acute respiratory distress syndrome.
Growing evidence suggests that acute respiratory distress syndrome (ARDS) occurring as a consequence of primary (direct) lung injury differs from that resulting from secondary (indirect) lung injury in terms of radiographic appearance, response to interventions, and outcomes. We examined whether there are differences in quality of life (QOL) in survivors of ARDS attributable to the mechanism of underlying lung injury. ⋯ QOL in survivors of ARDS appears to be influenced by the mechanism of lung injury (primary vs. secondary), lending support to the concept that ARDS is a heterogeneous condition.