Intensive care medicine
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Intensive care medicine · Feb 2015
Multicenter StudyDamage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage.
To determine the effectiveness of blood component therapy in the correction of trauma-induced coagulopathy during hemorrhage. ⋯ Damage control resuscitation with standard doses of blood components did not consistently correct trauma-induced coagulopathy during hemorrhage. There is an important opportunity to improve TIC management during damage control resuscitation.
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Dysglycemia is a characteristic feature of critical illness associated with adverse outcome. Whether dysglycemia contributes to brain dysfunction during critical illness and long-term neurological complications is unclear. We give an overview of glucose metabolism in the brain and review the literature on critical illness-induced dysglycemia and the brain. ⋯ Preventing hyperglycemia during critical illness holds promise as a neuroprotective strategy to preserve brain cell viability and prevent acute brain dysfunction and long-term cognitive impairment in survivors.
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Intensive care medicine · Feb 2015
Multicenter Study Observational StudyIncidence, characteristics and outcome of ICU-acquired candidemia in India.
A systematic epidemiological study on intensive care unit (ICU)-acquired candidemia across India. ⋯ The study highlighted a high burden of candidemia in Indian ICUs, early onset after ICU admission, higher risk despite less severe physiology score at admission and a vast spectrum of agents causing the disease with predominance of C. tropicalis.