Intensive care medicine
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Intensive care medicine · Feb 2015
Chloride-liberal vs. chloride-restrictive intravenous fluid administration and acute kidney injury: an extended analysis.
In a previous study, restricting intravenous chloride administration in ICU patients decreased the incidence of acute kidney injury (AKI). To test the robustness of this finding, we extended our observation period to 12 months. ⋯ On extended assessment, the overall impact of restricting chloride-rich fluids on AKI remained. However, sensitivity analysis suggested that other unidentified confounders may have also contributed to fluctuations in the incidence of AKI.