Intensive care medicine
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Intensive care medicine · Jun 2015
Randomized Controlled Trial Multicenter StudyEarly use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis: a multicenter randomized control trial.
To test whether the polymyxin B hemoperfusion (PMX HP) fiber column reduces mortality and organ failure in peritonitis-induced septic shock (SS) from abdominal infections. ⋯ This multicenter randomized controlled study demonstrated a non-significant increase in mortality and no improvement in organ failure with PMX HP treatment compared to conventional treatment of peritonitis-induced SS.