Intensive care medicine
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Intensive care medicine · Jun 2015
Randomized Controlled Trial Multicenter StudyEarly use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis: a multicenter randomized control trial.
To test whether the polymyxin B hemoperfusion (PMX HP) fiber column reduces mortality and organ failure in peritonitis-induced septic shock (SS) from abdominal infections. ⋯ This multicenter randomized controlled study demonstrated a non-significant increase in mortality and no improvement in organ failure with PMX HP treatment compared to conventional treatment of peritonitis-induced SS.
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Intensive care medicine · Jun 2015
Multicenter StudyMultinational development and validation of an early prediction model for delirium in ICU patients.
Delirium incidence in intensive care unit (ICU) patients is high and associated with poor outcome. Identification of high-risk patients may facilitate its prevention. ⋯ Patients' delirium risk for the complete ICU length of stay can be predicted at admission using the E-PRE-DELIRIC model, allowing early preventive interventions aimed to reduce incidence and severity of ICU delirium.
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Intensive care medicine · Jun 2015
Randomized Controlled TrialIntensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study.
To compare the effect of intensive versus conventional blood glucose control in patients with traumatic brain injury. ⋯ Although patients with traumatic brain injury randomly assigned to intensive compared to conventional glucose control experienced moderate and severe hypoglycemia more frequently, we found no significant difference in clinically important outcomes.