Intensive care medicine
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Intensive care medicine · Mar 2020
Observational StudyUse of combined cardiac and lung ultrasound to predict weaning failure in elderly, high-risk cardiac patients: a pilot study.
Weaning failure from mechanical ventilation may be due to lung de-recruitment or weaning-induced pulmonary oedema (WIPO). Both can be diagnosed by lung ultrasound (LUS) and transthoracic echocardiography (TTE), respectively. We conducted a prospective observational study, combining TTE and LUS, to determine if LUS alone may identify elderly patients at high risk of weaning or extubation failure. ⋯ ClinicalTrials.gov No. NCT03261440.
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Intensive care medicine · Mar 2020
Multicenter StudyBenefit-to-risk balance of bronchoalveolar lavage in the critically ill. A prospective, multicenter cohort study.
To assess the benefit-to-risk balance of bronchoalveolar lavage (BAL) in intensive care unit (ICU) patients. ⋯ Adverse events related to BAL in ICU patients are not infrequent nor necessarily benign. Our findings call for an extreme caution, when envisaging a BAL in ICU patients and for a mandatory accompaniment of the less experienced physicians.
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Intensive care medicine · Mar 2020
C-reactive protein clustering to clarify persistent inflammation, immunosuppression and catabolism syndrome.
Among patients surviving treatment in intensive care units (ICU), some cases exist for which inflammation persisted with prolonged hospital stays, referred as persistent inflammatory, immunosuppressed, catabolic syndrome (PIICS). C reactive protein (CRP) is regarded as the most important marker for PIICS. Nevertheless, the applicable cut-off of CRP for PIICS has never been described in the literature. ⋯ Among patients with prolonged hospital stay, the PIICS population had elevated CRP, but lower Barthel Index, albumin, and total lymphocyte counts. The criterion of day 14 CRP for PIICS should be 3.0 mg/dl.
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Intensive care medicine · Mar 2020
Correction to: Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura.
The original version of this article unfortunately contained a mistake. The penultimate row of Table 4 shows INR > 1.5 which is incorrect. ⋯ The authors apologize for the mistake. The correct table is given below.