Intensive care medicine
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Intensive care medicine · Mar 2020
C-reactive protein clustering to clarify persistent inflammation, immunosuppression and catabolism syndrome.
Among patients surviving treatment in intensive care units (ICU), some cases exist for which inflammation persisted with prolonged hospital stays, referred as persistent inflammatory, immunosuppressed, catabolic syndrome (PIICS). C reactive protein (CRP) is regarded as the most important marker for PIICS. Nevertheless, the applicable cut-off of CRP for PIICS has never been described in the literature. ⋯ Among patients with prolonged hospital stay, the PIICS population had elevated CRP, but lower Barthel Index, albumin, and total lymphocyte counts. The criterion of day 14 CRP for PIICS should be 3.0 mg/dl.
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Intensive care medicine · Mar 2020
Early diagnosis of bloodstream infections in the intensive care unit using machine-learning algorithms.
We aimed to develop a machine-learning (ML) algorithm that can predict intensive care unit (ICU)-acquired bloodstream infections (BSI) among patients suspected of infection in the ICU. ⋯ An ML approach that uses temporal and site-specific data achieved high performance in recognizing BC samples with a high probability for ICU-acquired BSI.
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Intensive care medicine · Mar 2020
Correction to: Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura.
The original version of this article unfortunately contained a mistake. The penultimate row of Table 4 shows INR > 1.5 which is incorrect. ⋯ The authors apologize for the mistake. The correct table is given below.