Intensive care medicine
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Intensive care medicine · Jun 2020
Multicenter StudySedation practice and discomfort during withdrawal of mechanical ventilation in critically ill patients at end-of-life: a post-hoc analysis of a multicenter study.
Little is known on the incidence of discomfort during the end-of-life of intensive care unit (ICU) patients and the impact of sedation on such discomfort. The aim of this study was to assess the incidence of discomfort events according to levels of sedation. ⋯ Discomfort was frequent during end-of-life of ICU patients and was mainly associated with extubation and less profound sedation.