Intensive care medicine
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Intensive care medicine · Jun 2020
ReviewAntimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper.
This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill adult patients in the intensive care unit (ICU). This Position Paper also provides a practical guide on how TDM can be applied in routine clinical practice to improve therapeutic outcomes in critically ill adult patients. ⋯ Although TDM should be the standard of care for most antimicrobials in every ICU, important barriers need to be addressed before routine TDM can be widely employed worldwide.
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Intensive care medicine · Jun 2020
Multicenter StudySedation practice and discomfort during withdrawal of mechanical ventilation in critically ill patients at end-of-life: a post-hoc analysis of a multicenter study.
Little is known on the incidence of discomfort during the end-of-life of intensive care unit (ICU) patients and the impact of sedation on such discomfort. The aim of this study was to assess the incidence of discomfort events according to levels of sedation. ⋯ Discomfort was frequent during end-of-life of ICU patients and was mainly associated with extubation and less profound sedation.
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Intensive care medicine · Jun 2020
Correction to: Clinical features and short-term outcomes of 18 patients with corona virus disease 2019 in intensive care unit.
The original version of this article unfortunately contained a mistake. There was an error in Xiaorong Hu's name. The original article has been corrected. The authors apologize for the mistake.