Intensive care medicine
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Intensive care medicine · Jun 2001
Multicenter StudyEvaluation of the logistic organ dysfunction system for the assessment of organ dysfunction and mortality in critically ill patients.
To evaluate the performance of the logistic organ dysfunction (LOD) system for the assessment of morbidity and mortality in multiple organ dysfunction/failure (MOD/F) in an independent database and to evaluate the use of sequential LOD measurements for the prediction of outcome. ⋯ The LOD system is well correlated well with the numbers and levels of organ dysfunctions and discriminates well between survivors and nonsurvivors. It can thus be used to quantify the baseline severity of organ dysfunction. Moreover, after customization of the predictive equation the LOD predicted hospital mortality in our patients with high precision. It thus provides a combined measure of morbidity and mortality for critically ill patients with MOD/F.
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To detect myocardial damage in severe systemic inflammation by cTnI measurements in patients without acute coronary syndromes. ⋯ Cardiac troponin I was elevated in 85% of patients with sepsis, septic shock or SIRS in our study. A high percentage showed infection caused by S. pneumoniae. In what way microorganisms cause cTnI elevations is not yet understood.
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Intensive care medicine · Jun 2001
Comparative StudySurvival and quality of life 12 years after ICU. A comparison with the general Norwegian population.
To study the long-term (12 year) survival and quality of life (QOL) in former ICU patients. ⋯ Our findings indicate that the long-term outcome after ICU is good, with an acceptable QOL and a life expectancy comparable with the general population in survivors 2 years after the ICU stay.
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Intensive care medicine · Jun 2001
Comparative StudyIntermittent versus continuous renal replacement therapy in the ICU: impact on electrolyte and acid-base balance.
The maintenance of normal serum sodium, potassium and bicarbonate concentrations is a therapeutic goal of renal replacement therapy (RRT) in acute renal failure (ARF). The aim of this study was to determine whether this goal is best achieved with intermittent hemodialysis (IHD) or continuous venovenous hemodiafiltration (CVVHDF). ⋯ Serum sodium and potassium, and arterial bicarbonate, concentrations are frequently abnormal in ARF patients before and during renal replacement. Normalization of these values, however, is achieved more frequently with CVVHDF than with IHD.
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Intensive care medicine · Jun 2001
Clinical TrialIs a short trial of prone positioning sufficient to predict the improvement in oxygenation in patients with acute respiratory distress syndrome?
To determine whether a 1-h trial of prone positioning is sufficient to identify responders. ⋯ A short-term trial of prone positioning does not appear a sufficient method to identify patients who would benefit from the postural treatment.