Intensive care medicine
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Intensive care medicine · Jun 2001
Multicenter StudyAccuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h.
In most databases used to build general severity scores the median duration of intensive care unit (ICU) stay is less than 3 days. Consequently, these scores are not the most appropriate tools for measuring prognosis in studies dealing with ICU patients hospitalized for more than 72 h. ⋯ The new model using SAPS II and LOD and their evolution during the first calendar days has good discrimination and calibration properties. We propose its use for benchmarking and evaluating the over-risk of death associated with ICU-acquired nosocomial infections.
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Intensive care medicine · Jun 2001
Randomized Controlled Trial Clinical TrialHigh-volume haemofiltration in human septic shock.
To evaluate whether high volume haemofiltration improves haemodynamics and affects serum cytokine and complement concentrations in human septic shock. ⋯ HVHF decreases vasopressor requirements in human septic shock and affects anaphylatoxin levels differently than standard CVVH.
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Intensive care medicine · Jun 2001
Multicenter StudyEvaluation of the logistic organ dysfunction system for the assessment of organ dysfunction and mortality in critically ill patients.
To evaluate the performance of the logistic organ dysfunction (LOD) system for the assessment of morbidity and mortality in multiple organ dysfunction/failure (MOD/F) in an independent database and to evaluate the use of sequential LOD measurements for the prediction of outcome. ⋯ The LOD system is well correlated well with the numbers and levels of organ dysfunctions and discriminates well between survivors and nonsurvivors. It can thus be used to quantify the baseline severity of organ dysfunction. Moreover, after customization of the predictive equation the LOD predicted hospital mortality in our patients with high precision. It thus provides a combined measure of morbidity and mortality for critically ill patients with MOD/F.
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To detect myocardial damage in severe systemic inflammation by cTnI measurements in patients without acute coronary syndromes. ⋯ Cardiac troponin I was elevated in 85% of patients with sepsis, septic shock or SIRS in our study. A high percentage showed infection caused by S. pneumoniae. In what way microorganisms cause cTnI elevations is not yet understood.
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Intensive care medicine · Jun 2001
Comparative StudySurvival and quality of life 12 years after ICU. A comparison with the general Norwegian population.
To study the long-term (12 year) survival and quality of life (QOL) in former ICU patients. ⋯ Our findings indicate that the long-term outcome after ICU is good, with an acceptable QOL and a life expectancy comparable with the general population in survivors 2 years after the ICU stay.