Actas urologicas españolas
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Bilateral scrotal vasectomy with double ligature and deferent duct section was performed in 55 male Wistar rats randomly assigned to three groups: control, simulated and experimental, which were studied after 1, 2, 6, 10 and 14 weeks post-vasectomy. At 6 weeks after vasectomy testicular atrophy, destructuration of epithelium germination, absence of spermatozoa, thickening and folding of tubular membrane were observed as well as a large dilation of interstitial space, features that are all increased after 10 and 14 weeks.