Clinical therapeutics
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Clinical therapeutics · Jan 2001
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialComparison of the efficacy of extended-release clarithromycin tablets and amoxicillin/clavulanate tablets in the treatment of acute exacerbation of chronic bronchitis.
Clarithromycin has established efficacy and safety in the treatment of respiratory infections. ⋯ The results of this study demonstrate the clinical and bacteriologic equivalence and improved gastrointestinal tolerability of a 7-day course of once-daily extended-release clarithromycin relative to a 10-day course of twice-daily amoxicillin/clavulanate in the treatment of AECB.